Description

2-Ethoxymethylene-3-Oxobutanenitrile is a versatile cyanoacetate derivative and a key reactive intermediate in organic synthesis. Its molecular structure, featuring both an ethoxymethylene and a nitrile group adjacent to a ketone, makes it a valuable building block for constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to streamline synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyridine, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for the introduction of specific functional groups.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and specialty chemicals requiring complex molecular architectures.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and advanced materials.

Basic Information

Product Name	2-Ethoxymethylene-3-Oxobutanenitrile
CAS No.	105224-25-7
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	2-(Ethoxymethylene)-3-oxobutanenitrile; 3-Oxobutanenitrile, 2-(ethoxymethylene)-; Ethyl (cyanomethylidene)acetate; 2-Cyano-3-ethoxybut-2-enoic acid methyl ester (tautomeric form); Cyanoacetic acid ethoxymethylene ester; Ethoxymethylenemalononitrile derivative
EINECS	Contact for details

Quality Control

Our 2-Ethoxymethylene-3-Oxobutanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.