Description

Bis(tert-Butyldicylcohexylphosphine)Dichloropalladium(II) is a highly active and selective palladium catalyst, widely recognized for its superior performance in cross-coupling reactions. Its value lies in enabling efficient and reliable synthesis of complex organic molecules, which is critical for research and commercial-scale production. This catalyst is essential for pharmaceutical R&D, agrochemical manufacturing, and advanced materials science, where precise and robust catalytic performance is required.

Application

This catalyst is a cornerstone in modern synthetic chemistry, enabling a wide range of transformations. Key applications include:

• Suzuki-Miyaura Cross-Coupling: For the formation of carbon-carbon bonds between aryl/vinyl boronic acids and halides, crucial for synthesizing biaryl compounds used in pharmaceuticals and OLED materials.
• Buchwald-Hartwig Amination: For the coupling of amines with aryl halides, a fundamental reaction in the synthesis of drug candidates and fine chemicals containing nitrogen.
• Heck Reaction (Mizoroki-Heck): For the coupling of alkenes with aryl/vinyl halides, important for creating styrene derivatives and other unsaturated compounds.
• Sonogashira Coupling: For the synthesis of internal alkynes by coupling terminal alkynes with aryl or vinyl halides.
• Academic & Industrial R&D: As a reliable catalyst for method development and the synthesis of novel chemical entities in research laboratories.
• Scale-up Process Chemistry: For the transition from laboratory-scale discovery to pilot plant and commercial manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Bis(tert-Butyldicylcohexylphosphine)Dichloropalladium(II)
CAS No.	104889-13-6
Molecular Formula	C28H56Cl2P2Pd
Molecular Weight	640.98 g/mol
Synonyms	Bis(di-tert-butylcyclohexylphosphine)palladium(II) dichloride; Di-tert-butylcyclohexylphosphine palladium(II) dichloride; Pd(dtbpf)Cl2; Pd(dtbpfc)Cl2; Dichlorobis(di-tert-butylcyclohexylphosphine)palladium; Palladium(II) dichloride bis(di-tert-butylcyclohexylphosphine) complex; Pd-132 (common trade designation)
EINECS	Contact for details

Quality Control

Our Bis(tert-Butyldicylcohexylphosphine)Dichloropalladium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot undergoes rigorous analytical testing, including assay and impurity profiling, to meet the exacting standards required for sensitive cross-coupling chemistry. Certificates of Analysis (COA) detailing purity, metal content, and spectroscopic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd Content)	≥ 16.5 %
Purity (HPLC)	≥ 98.0 %
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.