Description

Methyl Pentafluoropropionylacetate is a high-value fluorinated building block and reagent. This specialty ester is critical for introducing the pentafluoropropionyl moiety into target molecules, enabling the synthesis of advanced materials and bioactive compounds with tailored properties. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require precise fluorination to modify solubility, stability, and biological activity.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Serves as a key reagent for creating novel fluorinated pesticides and herbicides with improved efficacy and environmental profile.
• Material Science: Employed in the production of fluorinated polymers, coatings, and liquid crystals to impart oil/water repellency and chemical resistance.
• Analytical Chemistry: Acts as a derivatization agent in gas chromatography (GC) and mass spectrometry (MS) for the analysis of complex mixtures.
• Organic Synthesis: A versatile building block for constructing complex molecules via reactions such as Claisen condensations and nucleophilic substitutions.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve high-voltage stability and safety.

Basic Information

Product Name	Methyl Pentafluoropropionylacetate
CAS No.	104857-88-7
Molecular Formula	C7H5F5O3
Molecular Weight	232.11 g/mol
Synonyms	Methyl 4,4,4,5,5,5-hexafluoro-3-oxopentanoate; Methyl 3-oxo-4,4,4,5,5,5-hexafluoropentanoate; 4,4,4,5,5,5-Hexafluoro-3-oxopentanoic acid methyl ester; Methyl perfluoropropionylacetate; Methyl 2-(pentafluoropropanoyl)acetate; Pentafluoropropionylacetic acid methyl ester; MPFPA; HFA Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl Pentafluoropropionylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.350 - 1.370
Density (20°C)	1.45 - 1.55 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.