Description

2-Bromo-1-(5-Methyl-3-Phenylisoxazol-4-Yl)Ethan-1-One is a high-value brominated isoxazole derivative, a crucial synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a versatile building block for constructing complex heterocyclic scaffolds, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazole moiety.
• Chemical Biology Probe Synthesis: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential intermediate for synthesizing specialty polymers or organic electronic materials with specific optoelectronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.
• Custom Synthesis & Scale-Up: A starting material for contract manufacturing organizations (CMOs) engaged in producing complex molecules for clinical trials or commercial supply.

Basic Information

Item	Details
Product Name	2-Bromo-1-(5-Methyl-3-Phenylisoxazol-4-Yl)Ethan-1-One
CAS No.	104777-39-1
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	2-Bromo-1-(5-methyl-3-phenyl-4-isoxazolyl)ethanone; 4-Acetyl-5-methyl-3-phenylisoxazole, 2-bromo derivative; α-Bromo-5-methyl-3-phenylisoxazole-4-acetophenone; 2-Bromo-1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)ethan-1-one; Bromomethyl 5-methyl-3-phenylisoxazol-4-yl ketone; 104777-39-1; Ethanone, 2-bromo-1-(5-methyl-3-phenyl-4-isoxazolyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Methyl-3-Phenylisoxazol-4-Yl)Ethan-1-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture uptake. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.