Description

(2S,3S)-2-Benzyloxy-3,4-o-Isopropylidene-Butan-1-Ol CAS NO 104322-67-0 is a high-purity chiral building block and protected sugar derivative, essential for the synthesis of complex pharmaceutical intermediates and fine chemicals. Its defined stereochemistry and protective groups make it a critical starting material for researchers and process chemists requiring precise molecular architecture. This compound is primarily utilized in the development of active pharmaceutical ingredients (APIs), nucleoside analogs, and other specialty organic molecules where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Asymmetric Synthesis: Used as a building block for constructing complex natural products and bioactive molecules with defined stereocenters.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for the preparation of glycosides, oligosaccharides, and glycomimetics.
• Process Chemistry & Scale-up: Employed in the development and optimization of commercial-scale synthetic routes for advanced intermediates.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	(2S,3S)-2-Benzyloxy-3,4-o-Isopropylidene-Butan-1-Ol
CAS No.	104322-67-0
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	(2S,3S)-2-(Benzyloxy)-3,4-O-isopropylidene-1-butanol; (3S,4S)-4-(Benzyloxymethyl)-2,2-dimethyl-1,3-dioxolane; 1,2-O-Isopropylidene-3-O-benzyl-L-threitol; 3-O-Benzyl-1,2-O-isopropylidene-L-threitol; L-Threitol, 3-O-benzyl-1,2-O-isopropylidene-; (2S,3S)-2-Benzyloxy-3,4-isopropylidenedioxybutan-1-ol
EINECS	Contact for details

Quality Control

Our production of (2S,3S)-2-Benzyloxy-3,4-o-Isopropylidene-Butan-1-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.