Description

(1S)-(+)-(Camphorylsulfonyl)Oxaziridine is a high-purity, chiral oxaziridine reagent widely recognized for its role as a versatile electrophilic oxygen transfer agent. Its value lies in enabling highly stereoselective oxidation reactions, crucial for synthesizing complex chiral intermediates in pharmaceutical and fine chemical research. This compound is essential for chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance reagents for asymmetric synthesis.

Application

• Asymmetric Synthesis: Key reagent for the stereoselective oxidation of sulfides to sulfoxides and for the hydroxylation of enolates.
• Pharmaceutical Intermediates: Used in the production of chiral active pharmaceutical ingredients (APIs), particularly for drugs requiring specific stereochemistry.
• Agrochemical Research: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Facilitates the production of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic & Process Chemistry: A valuable tool in methodological development and scale-up studies for novel oxidation protocols.
• Material Science: Potential use in the synthesis of chiral polymers or ligands for catalysis.

Basic Information

Product Name	(1S)-(+)-(Camphorylsulfonyl)Oxaziridine
CAS No.	104322-63-6
Molecular Formula	C10H15NO3S
Molecular Weight	229.30 g/mol
Synonyms	(+)-(1S)-Camphorsulfonyl Oxaziridine; (1S)-(+)-10-Camphorsulfonyl Oxaziridine; (S)-(+)-Camphorsulfonyloxaziridine; Davis Reagent; (S)-(+)-2-(Camphorsulfonyl)-3-phenyloxaziridine (Note: The phenyl variant is a common related compound); (1S,4R)-(+)-10-(Camphorsulfonyl)oxaziridine; CSO; (S)-CSO
EINECS	Contact for details

Quality Control

Our (1S)-(+)-(Camphorylsulfonyl)Oxaziridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high optical purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and polarimetry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.