Description

4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonaldehyde is a highly fluorinated, reactive aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethylated crotonaldehyde backbone, makes it a versatile precursor for introducing fluorinated motifs into target molecules, which is crucial for modulating their physical, chemical, and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated heterocycles and complex molecules with potential therapeutic activity.
• Agrochemical Research: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can enhance stability, bioavailability, and efficacy.
• Material Science Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and specialty coatings with unique surface properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions, nucleophilic additions, and other transformations to construct complex, value-added fluoroorganic compounds.
• Fluorine Chemistry Research: An important compound for academic and industrial research into new methodologies for C-F bond formation and fluorinated scaffold assembly.

Basic Information

Product Name	4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonaldehyde
CAS No.	104291-39-6
Molecular Formula	C5H2F6O
Molecular Weight	192.06 g/mol
Synonyms	4,4,4-Trifluoro-3-(trifluoromethyl)-2-butenal; (E)-4,4,4-Trifluoro-3-(trifluoromethyl)but-2-enal; 3-(Trifluoromethyl)-4,4,4-trifluorocrotonaldehyde; 4,4,4-Trifluoro-3-trifluoromethylcrotonaldehyde; Perfluoroisocrotonaldehyde; TFCA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-3-(Trifluoromethyl)Crotonaldehyde is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical research and development processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, it is recommended to store at 2-8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.