Description

2(1H)-Naphthalenone, 6-Fluoro-3,4-Dihydro-1-(1-Methylethyl)- is a specialized fluorinated naphthalenone derivative, serving as a critical advanced pharmaceutical intermediate in modern synthetic chemistry. Its unique structure, featuring a fluorine atom and an isopropyl group, makes it a valuable building block for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high-purity, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the fluorine moiety for enhanced bioactivity and stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex fused-ring systems and fluorinated heterocycles.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) and metabolic stability in medicinal chemistry.

Basic Information

Product Name	2(1H)-Naphthalenone, 6-Fluoro-3,4-Dihydro-1-(1-Methylethyl)-
CAS No.	104204-91-3
Molecular Formula	C₁₃H₁₃FO
Molecular Weight	204.24 g/mol
Synonyms	6-Fluoro-1-isopropyl-3,4-dihydronaphthalen-2(1H)-one; 6-Fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-one; 1-Isopropyl-6-fluoro-3,4-dihydro-2(1H)-naphthalenone; 6-Fluoro-1-(propan-2-yl)-3,4-dihydro-2H-naphthalen-1-one; 104204-91-3; Fluorinated dihydronaphthalenone; Isopropyl-fluoronaphthalenone
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Naphthalenone, 6-Fluoro-3,4-Dihydro-1-(1-Methylethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.