Description

4-Chloro-1-(4-Chlorophenyl)-2-Fluorobutan-1-One is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Used in the synthesis of fluorinated components for liquid crystal displays (LCDs), where its structure contributes to desired dielectric anisotropy and viscosity.
• Organic Electronics: Acts as a precursor for materials used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new fluorination methodologies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals for client-specific projects.

Basic Information

Product Name	4-Chloro-1-(4-Chlorophenyl)-2-Fluorobutan-1-One
CAS No.	104110-81-8
Molecular Formula	C10H9Cl2FO
Molecular Weight	235.08 g/mol
Synonyms	1-(4-Chlorophenyl)-4-chloro-2-fluorobutan-1-one; 4-Chloro-2-fluoro-1-(4-chlorophenyl)butan-1-one; 2-Fluoro-4-chloro-1-(4-chlorophenyl)butan-1-one; 4-Chloro-1-(p-chlorophenyl)-2-fluorobutan-1-one; p-Chlorophenyl 4-chloro-2-fluorobutyl ketone; 4-Chloro-2-fluorobutyrophenone, 4'-chloro derivative; (4-Chlorophenyl)(4-chloro-2-fluorobutyl) ketone
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-(4-Chlorophenyl)-2-Fluorobutan-1-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.