Description

1H-Pyrrolizine-1-Carboxaldehyde, Hexahydro-3-Oxo-, (1R-Cis)- (9Ci) is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of complex, biologically active molecules, offering a defined stereocenter critical for enantioselective drug development. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries in structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a precursor for catalysts or ligands used in enantioselective transformations.
• Process Development: Employed in the scale-up and optimization of synthetic routes for potential new drugs.
• Academic Research: Utilized in organic chemistry and chemical biology research for exploring new synthetic methodologies.

Basic Information

Product Name	1H-Pyrrolizine-1-Carboxaldehyde, Hexahydro-3-Oxo-, (1R-Cis)- (9Ci)
CAS No.	103979-75-5
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	(1R,5S)-1-Formyl-3-oxo-2,6-diazabicyclo[3.3.0]octane; Hexahydro-3-oxo-1H-pyrrolizine-1-carboxaldehyde, (1R-cis)-; (1R,5S)-1-Formyl-3-oxo-2,6-diazabicyclo[3.3.0]octane; 1H-Pyrrolizine-1-carboxaldehyde, hexahydro-3-oxo-, (1R,5S)-; (1R,5S)-1-Carbaldehyde-3-oxo-2,6-diazabicyclo[3.3.0]octane; 2,6-Diazabicyclo[3.3.0]octane-1-carboxaldehyde, 3-oxo-, (1R,5S)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and development use. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and specific parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (HPLC, Area %)	≥97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.