Description

2-Bromoethyl Trifluoromethanesulphonate is a versatile and highly reactive alkylating agent, primarily valued for its role as a key trifluoromethanesulfonate (triflate) ester intermediate in advanced organic synthesis. Its core value proposition lies in its ability to efficiently introduce the 2-bromoethyl moiety into target molecules, enabling the construction of complex chemical architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those requiring functionalized ethyl linkers or halogenated side chains.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the bromoethyl group acts as a key functional handle.
• Material Science: Employed in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: Serves as an effective electrophile in various metal-catalyzed cross-coupling reactions, such as Suzuki and Negishi couplings.
• Nucleoside & Nucleotide Chemistry: Useful for the modification of nucleosides and the synthesis of nucleotide analogs in medicinal chemistry.
• Fluorination Chemistry: Acts as a precursor or reagent in pathways designed to introduce fluorine-containing groups into organic molecules.

Basic Information

Product Name	2-Bromoethyl Trifluoromethanesulphonate
CAS No.	103935-47-3
Molecular Formula	C3H4BrF3O3S
Molecular Weight	257.02 g/mol
Synonyms	2-Bromoethyl Triflate; Trifluoromethanesulfonic Acid 2-Bromoethyl Ester; 2-Bromoethyl Trifluoromethanesulfonate; 2-Bromoethyl Trifluoromethylsulfonate; 2-Bromoethyl Trifluorosulfonate; 2-Bromoethanol Triflate; 1-Bromo-2-[(trifluoromethyl)sulfonyloxy]ethane
EINECS	Contact for details

Quality Control

Every batch of 2-Bromoethyl Trifluoromethanesulphonate is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.