Description

Methanone, (1-Fluorocyclopropyl)(4-Methoxyphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif combining a fluorinated cyclopropane ring with a methoxyphenyl group, offering a valuable handle for modulating the physicochemical properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated cyclopropyl motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorinated cyclopropane unit can improve activity and environmental profile.
• Material Science Precursor: Serves as a building block for advanced organic materials, such as liquid crystals or polymers with tailored electronic or optical properties.
• Medicinal Chemistry Probe: Employed in structure-activity relationship (SAR) studies to investigate the role of fluorinated and constrained ring systems in biological activity.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Methanone, (1-Fluorocyclopropyl)(4-Methoxyphenyl)- (9Ci)
CAS No.	103543-85-7
Molecular Formula	C11H11FO2
Molecular Weight	194.20 g/mol
Synonyms	(1-Fluorocyclopropyl)(4-methoxyphenyl)methanone; 4-Methoxy-(1-fluorocyclopropyl)phenyl ketone; 1-Fluorocyclopropyl 4-methoxyphenyl ketone; (4-Methoxyphenyl)(1-fluorocyclopropyl)methanone; p-Methoxy-1-fluorocyclopropyl phenyl ketone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. For specific pharmacopeial (USP/EP) or custom grade requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.