Description

Methanone, (4-Chlorophenyl)(1-Fluorocyclopropyl)- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a chlorophenyl and a fluorinated cyclopropyl moiety, makes it a valuable precursor for creating complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the fluorine and chlorine substituents.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry for the creation of novel ligands and catalysts used in asymmetric synthesis and coupling reactions.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding the effects of fluorinated cyclopropanes on molecular conformation and reactivity.

Basic Information

Product Name	Methanone, (4-Chlorophenyl)(1-Fluorocyclopropyl)- (9Ci)
CAS No.	103543-60-8
Molecular Formula	C10H8ClFO
Molecular Weight	198.62 g/mol
Synonyms	(4-Chlorophenyl)(1-Fluorocyclopropyl)methanone; 1-Fluoro-1-cyclopropyl(4-chlorophenyl)methanone; 4-Chloro-α-(1-fluorocyclopropyl)benzyl alcohol ketone; (p-Chlorophenyl)(1-fluorocyclopropyl) ketone; 1-(4-Chlorophenyl)-2-fluoro-1-cyclopropylethanone; 103543-60-8; (4-Chlorophenyl)(fluorocyclopropyl)methanone
EINECS	Contact for details

Quality Control

Our Methanone, (4-Chlorophenyl)(1-Fluorocyclopropyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.