Description

7-Fluoro-2H-1,4-Benzoxazin-3(4H)-One is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the fluorine atom and benzoxazinone core impart desirable biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical scaffold for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated benzoxazinone structure.
• Organic Light-Emitting Diode (OLED) Materials: Serves as an electron-transport or host material precursor due to its rigid, planar conjugated system.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands for catalytic applications in asymmetric synthesis.
• Academic and Industrial R&D: A versatile building block for methodological studies in fluorination chemistry and heterocycle formation.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Item	Details
Product Name	7-Fluoro-2H-1,4-Benzoxazin-3(4H)-One
CAS No.	103361-99-5
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	7-Fluoro-3,4-dihydro-2H-1,4-benzoxazin-3-one; 7-Fluoro-3,4-dihydro-1,4-benzoxazin-3-one; 7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one; 7-Fluoro-4H-1,4-benzoxazin-3-one; 103361-99-5; 7-Fluoro-1,4-benzoxazin-3-one; 7-Fluorobenzoxazinone
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2H-1,4-Benzoxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.