Description

1-(2-Bromo-4-Methylphenyl)Ethanone is a specialized brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive halogen site and a carbonyl group, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity intermediates for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where its bromine atom facilitates further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors and photoactive materials for electronic applications.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Academic and R&D Laboratories: Used in methodological research and for exploring new chemical reactions and pathways.

Basic Information

Product Name	1-(2-Bromo-4-Methylphenyl)Ethanone
CAS No.	103286-27-7
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	2'-Bromo-4'-methylacetophenone; 2-Bromo-4-methylacetophenone; 1-Acetyl-2-bromo-4-methylbenzene; 2-Bromo-4-methylphenylethanone; (2-Bromo-4-methylphenyl)ethan-1-one; 2-Bromo-p-methylacetophenone; α-Bromo-4-methylacetophenone (isomer); 4-Methyl-2-bromoacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Methylphenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.