Description

Anatoxin-A(S) is a potent, naturally occurring neurotoxin produced by certain species of cyanobacteria (blue-green algae). This compound is of significant interest for research purposes due to its unique mechanism of action as a potent and irreversible acetylcholinesterase inhibitor. It serves as a critical reference standard and tool compound for toxicologists, environmental scientists, and pharmacologists studying neurotoxicity, cyanobacterial blooms, and the development of detection methods.

Application

• Toxicological Research: Used as a reference standard in studies investigating the mechanisms of neurotoxicity, particularly those involving acetylcholinesterase inhibition.
• Environmental Monitoring: Critical for the calibration and validation of analytical methods (e.g., LC-MS/MS) to detect and quantify cyanotoxins in water samples from lakes, reservoirs, and recreational waters.
• Biomedical Research: Employed as a tool compound in neurological research to model cholinergic dysfunction and study potential antidotes or protective agents.
• Method Development: Serves as a key analyte for developing and optimizing new chromatographic and mass spectrometric techniques for toxin analysis.
• Quality Control & Assurance: Used by manufacturers and testing laboratories as a certified reference material (CRM) to ensure the accuracy and reliability of cyanotoxin test kits and analytical services.
• Regulatory Compliance & Safety: Supports public health agencies and water treatment facilities in risk assessment and establishing safety guidelines for cyanotoxins in drinking and recreational water.

Basic Information

Product Name	Anatoxin-A(S)
CAS No.	103170-78-1
Molecular Formula	C7H17N4O4P
Molecular Weight	252.21 g/mol
Synonyms	Anatoxin-a(s); Anatoxin A(S); (5S)-5-[(Hydroxymethylphosphinyl)oxy]-1,2,3,3a,4,5,6,7-octahydro-1H-pyrrolo[3,2-c]pyridin-1-one; Very Fast Death Factor (VFDF); Guanitoxin; GNT
EINECS	Contact for details

Quality Control

Our Anatoxin-A(S) is produced and handled under strict quality protocols suitable for research and analytical applications. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and stability. A comprehensive Certificate of Analysis (COA) is provided, detailing batch-specific results for purity, identification, and related substances. We support compliance with relevant quality frameworks for reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, consider storage under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. Keep the container tightly sealed and stored in a dedicated, well-ventilated freezer.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.