Description

(5Z)-7-[(1S,5R)-6,6-Dimethyl-3β-[(1-Oxohexyl)Amino]Bicyclo[3.1.1]Heptan-2α-Yl]-5-Heptenoic Acid is a high-purity, synthetically derived prostaglandin analog with a complex bicyclic structure. This compound is a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing treatments for inflammation, cardiovascular, and ocular conditions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel prostaglandin-based drugs targeting intraocular pressure (glaucoma), inflammation, and vasodilation.
• Biochemical Research: Used as a reference standard and active probe in pharmacological studies to investigate prostaglandin receptor (EP, FP) activity and signaling pathways.
• Process Development: Serves as a critical intermediate for process chemists during scale-up and optimization of active pharmaceutical ingredient (API) manufacturing routes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials and niche APIs.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry projects and the development of new synthetic methodologies for complex natural product analogs.

Basic Information

Product Name	(5Z)-7-[(1S,5R)-6,6-Dimethyl-3β-[(1-Oxohexyl)Amino]Bicyclo[3.1.1]Heptan-2α-Yl]-5-Heptenoic Acid
CAS No.	103081-25-0
Molecular Formula	C22H37NO3
Molecular Weight	363.54 g/mol
Synonyms	Latanoprost Related Compound A; Latanoprost Impurity A; 13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2α isopropyl ester impurity A; 7-[(1S,5R)-6,6-Dimethyl-3-(hexanoylamino)bicyclo[3.1.1]heptan-2-yl]-5Z-heptenoic acid; Prostaglandin F2α analog intermediate; Bicyclo[3.1.1]heptane prostaglandin derivative; 15-Deoxy-16-hydroxy-16-vinyl prostaglandin analog.
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with client specifications. Our quality commitment aligns with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is moisture-sensitive; allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.