Description

4-Fluoro-1-Benzosulfonyl-1H-Indole is a high-purity, synthetically valuable organic building block characterized by its indole core functionalized with a benzosulfonyl group and a fluorine atom. This compound matters as a versatile intermediate in advanced pharmaceutical research and fine chemical synthesis, enabling the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functional organic materials, including organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Academic Research: Utilized in university and institutional labs for methodological development in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	4-Fluoro-1-Benzosulfonyl-1H-Indole
CAS No.	102855-23-2
Molecular Formula	C₁₄H₁₀FNO₂S
Molecular Weight	275.30 g/mol
Synonyms	1-(Phenylsulfonyl)-4-fluoro-1H-indole; 4-Fluoro-1-(phenylsulfonyl)indole; 4-Fluoro-1H-indole, 1-(phenylsulfonyl)-; 4-Fluoroindole-1-benzenesulfonate; Benzenesulfonic acid, 4-fluoro-1H-indol-1-yl ester; 1-Benzenesulfonyl-4-fluoroindole; 4-Fluoro-1-benzenesulfonylindole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Benzosulfonyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to meeting the stringent requirements of research and development, and specifications can be aligned with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.