Description

Benzyl 2,3-o-Isopropylidene-α-D-Mannopentenofuranoside-6-Aldehyde is a key protected carbohydrate intermediate, specifically a mannose derivative with a reactive aldehyde functionality. This compound is essential for the controlled synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics, enabling precise structural modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for advanced glycosylation reactions and the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of nucleoside analogs, antiviral agents, and other glycosylated active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Used in academic and industrial R&D for constructing complex carbohydrate scaffolds, studying glycosidase inhibitors, and developing glycan-based probes.
• Oligosaccharide Synthesis: A versatile precursor for the stepwise assembly of defined oligosaccharide chains via its reactive aldehyde group for chain elongation or conjugation.
• Glycoconjugate Development: Employed in the creation of glycopeptides, glycolipids, and neoglycoproteins for vaccine development and targeted drug delivery systems.
• Chemical Biology Tools: Facilitates the production of labeled sugars and affinity tags for studying carbohydrate-protein interactions and cellular processes.

Basic Information

Product Name	Benzyl 2,3-o-Isopropylidene-α-D-Mannopentenofuranoside-6-Aldehyde
CAS No.	102854-75-1
Molecular Formula	C₁₅H₁₈O₆
Molecular Weight	294.30 g/mol
Synonyms	Benzyl 2,3-O-Isopropylidene-α-D-ribo-hexofuranosid-5-ulose; 6-Deoxy-6-oxo-benzyl 2,3-O-isopropylidene-α-D-mannofuranoside; Benzyl 2,3-O-Isopropylidene-α-D-mannofuranosid-6-ulose; 5-Aldehyde-1,2-O-isopropylidene-3-O-benzyl-α-D-ribofuranose; 6-Oxo-benzyl 2,3-di-O-isopropylidene-α-D-mannofuranoside (incorrect but common alias); Protected Mannose Aldehyde; Benzyl Isopropylidene Mannose Aldehyde
EINECS	Contact for details

Quality Control

Our Benzyl 2,3-o-Isopropylidene-α-D-Mannopentenofuranoside-6-Aldehyde is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.