Description

5-(2-Fluoro-Phenyl)-Cyclohexane-1,3-Dione is a high-purity fluorinated cyclic diketone building block, essential for advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring fused to a reactive 1,3-diketone moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Research: Serves as a building block for developing specialty polymers and organic electronic materials due to its conjugated system.
• Chemical Biology Probes: Employed in the creation of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.
• Catalyst Ligand Development: The diketone functionality can be utilized to develop novel chelating ligands for asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated intermediates.

Basic Information

Product Name	5-(2-Fluoro-Phenyl)-Cyclohexane-1,3-Dione
CAS No.	102821-72-7
Molecular Formula	C12H11FO2
Molecular Weight	206.21 g/mol
Synonyms	5-(2-Fluorophenyl)-1,3-cyclohexanedione; 2-Fluorophenyl-1,3-cyclohexanedione; 1,3-Cyclohexanedione, 5-(2-fluorophenyl)-; 5-(o-Fluorophenyl)cyclohexane-1,3-dione; 2-Fluoro-β,δ-dioxocyclohexanepropiophenone
EINECS	Contact for details

Quality Control

Our 5-(2-Fluoro-Phenyl)-Cyclohexane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.