Description

Alanine, n-Acetyl-3-((2-Chloro-2-Methylpropyl)Thio)-, Methyl Ester, L- is a specialized, high-purity chiral building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex peptide mimetics or enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in protease inhibitor programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Peptidomimetic Synthesis: Serves as a modified amino acid derivative for constructing non-natural peptides with enhanced stability or biological activity.
• Biochemical Tool Compound: Potential use in developing enzyme substrates or inhibitors for biochemical assays and proteomics research.
• Process Chemistry: Employed in route scouting and scale-up synthesis for GMP production of candidate drugs.
• Academic Research: Utilized in universities and institutes for studies in organic synthesis methodology and bioorganic chemistry.

Basic Information

Item	Details
Product Name	Alanine, n-Acetyl-3-((2-Chloro-2-Methylpropyl)Thio)-, Methyl Ester, L-
CAS No.	102516-58-5
Molecular Formula	C10H18ClNO3S
Molecular Weight	267.77 g/mol
Synonyms	L-Alanine, N-acetyl-3-[(2-chloro-2-methylpropyl)thio]-, methyl ester; N-Acetyl-S-(2-chloro-2-methylpropyl)-L-cysteine methyl ester; Methyl N-acetyl-3-((2-chloro-2-methylpropyl)thio)-L-alaninate; (2R)-2-Acetamido-3-[(2-chloro-2-methylpropyl)sulfanyl]propanoic acid methyl ester; Ac-Ala(SCMe2CH2Cl)-OMe; S-(2-Chloro-2-methylpropyl)-N-acetyl-L-cysteine methyl ester; Alanine derivative, CAS 102516-58-5
EINECS	Contact for details

Quality Control

Our Alanine, n-Acetyl-3-((2-Chloro-2-Methylpropyl)Thio)-, Methyl Ester, L- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.