Description

(3R)-4-Acetyl-1,3-Dihydro-1-Oxo-5-[(1S)-1,3,3-Trimethylcyclohexyl]Isobenzofuran-3-Ol Acetate is a high-purity, stereochemically defined synthetic intermediate of significant commercial interest. Its complex molecular architecture, featuring fused isobenzofuran and substituted cyclohexyl moieties, makes it a versatile chiral building block for advanced organic synthesis. This compound is primarily sought after by R&D and production teams in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Fine Chemical Synthesis: Used as a key building block for constructing sophisticated fragrance molecules, agrochemicals, and functional materials requiring specific stereochemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new stereoselective reactions.
• Process Chemistry Development: Utilized for scaling up synthetic routes in pilot plants and commercial manufacturing, where consistent quality is paramount.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in regulatory and analytical laboratories.

Basic Information

Product Name	(3R)-4-Acetyl-1,3-Dihydro-1-Oxo-5-[(1S)-1,3,3-Trimethylcyclohexyl]Isobenzofuran-3-Ol Acetate
CAS No.	102396-22-5
Molecular Formula	C23H30O5
Molecular Weight	386.48 g/mol
Synonyms	5-[(1S)-1,3,3-Trimethylcyclohexyl]-4-acetyl-1,3-dihydro-1-oxo-(3R)-isobenzofuran-3-ol acetate; (3R,5S)-4-Acetyl-1,3-dihydro-1-oxo-5-(1,3,3-trimethylcyclohexyl)isobenzofuran-3-yl acetate; Ambrial; Isobenzofuran derivative CAS 102396-22-5; (R)-4-Acetyl-1,3-dihydro-1-oxo-5-((S)-1,3,3-trimethylcyclohexyl)isobenzofuran-3-yl acetate
EINECS	Contact for details

Quality Control

Our production of (3R)-4-Acetyl-1,3-Dihydro-1-Oxo-5-[(1S)-1,3,3-Trimethylcyclohexyl]Isobenzofuran-3-Ol Acetate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to moisture and elevated temperatures.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.