Description

4-Bromo-2-Benzofuran-1(3H)-One is a versatile brominated benzofuranone derivative, a key heterocyclic building block prized for its reactive halogen functionality. This compound matters for its role as a crucial synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical and advanced material research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging the benzofuranone scaffold for biological activity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in the fabrication of advanced OLED displays and lighting.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis, useful in cross-coupling and other synthetic transformations.
• Polymer and Material Science: Incorporated into specialty polymers and advanced materials to impart specific electronic or photophysical properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	4-Bromo-2-Benzofuran-1(3H)-One
CAS No.	102308-43-0
Molecular Formula	C8H5BrO2
Molecular Weight	213.03 g/mol
Synonyms	4-Bromo-1,3-dihydro-2-benzofuran-1-one; 4-Bromo-2(3H)-benzofuranone; 4-Bromophthalide; 4-Bromo-1(3H)-isobenzofuranone; 4-Bromoisobenzofuran-1(3H)-one; 4-Bromo-3H-isobenzofuran-1-one; 4-Bromophthalan-1-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Benzofuran-1(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.