Description

3-Chloro-4-Methoxybenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and methoxy substituents, makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the chloro-methoxy pattern is a common pharmacophore.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes due to its rigid, polarizable structure.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of advanced colorants and photographic chemicals.
• Polymer Chemistry: Can be utilized as a monomer or modifier in the synthesis of high-performance polymers and resins.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, cyanation studies, and as a standard in method development.

Basic Information

Product Name	3-Chloro-4-Methoxybenzonitrile
CAS No.	102151-33-7
Molecular Formula	C8H6ClNO
Molecular Weight	167.59 g/mol
Synonyms	3-Chloro-4-methoxybenzonitrile; 4-Methoxy-3-chlorobenzonitrile; 3-Chloro-4-methoxybenzene carbonitrile; 3-Chloro-p-anisonitrile; 2-Chloro-4-cyanomethoxybenzene (ambiguous); Benzonitrile, 3-chloro-4-methoxy-; 102151-33-7 (CAS)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production of 3-Chloro-4-Methoxybenzonitrile adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods (HPLC, GC, NMR). Our quality system is designed to meet the exacting standards of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.