Description

(S)-3-Z-Amino-1-Diazo-5-Methyl-2-Hexanone is a specialized chiral diazo compound with a defined stereochemistry. This high-purity intermediate is critical for the synthesis of complex bioactive molecules, offering precise control over stereochemical outcomes in advanced chemical reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and fine chemicals, where its unique structure enables the construction of sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral active pharmaceutical ingredients (APIs) and investigational new drugs.
• Asymmetric Synthesis: Serves as a precursor for chiral auxiliaries or catalysts used in stereoselective transformations.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and constrained scaffolds for drug discovery.
• Agrochemical Development: Intermediate for creating novel, stereochemically-defined active ingredients for crop protection.
• Academic & Process Chemistry: Valuable reagent for methodological development and scaling up chiral synthetic routes.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(S)-3-Z-Amino-1-Diazo-5-Methyl-2-Hexanone
CAS No.	102123-81-9
Molecular Formula	C8H13N3O
Molecular Weight	167.21 g/mol
Synonyms	(S)-3-(Benzyloxycarbonylamino)-1-diazo-5-methyl-2-hexanone; (S)-Z-Amino-1-diazo-5-methyl-2-hexanone; (S)-3-(Cbz-Amino)-1-diazo-5-methylhexan-2-one; (S)-1-Diazo-3-[(phenylmethoxy)carbonyl]amino-5-methyl-2-hexanone; Cbz-Diazo-Leucine Ketone; N-Carbobenzoxy-L-diazo-leucine ketone; (S)-3-(N-Cbz-Amino)-1-diazo-5-methyl-2-hexanone
EINECS	Contact for details

Quality Control

Our (S)-3-Z-Amino-1-Diazo-5-Methyl-2-Hexanone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and diazo nature, prolonged exposure to light or heat should be avoided. Keep container sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.