Description

[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aβ-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is a complex, high-value indole alkaloid derivative characterized by its unique isocyano and chloro-substituted polycyclic structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile scaffold in synthetic organic chemistry for constructing novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and neurology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel, complex drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reagent: Serves as a specialized precursor for introducing the isocyano functional group into complex molecular architectures.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Academic Research: Valuable for methodological studies in total synthesis and the development of new catalytic reactions.

Basic Information

Item	Details
Product Name	[6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aβ-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole
CAS No.	102045-13-6
Molecular Formula	C22H27ClN2
Molecular Weight	354.92 g/mol
Synonyms	(-)-8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,6,6aα,7,8,9,10,10aβ-octahydronaphtho[1,2,3-cd]indole; 8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,3,6,6aα,7,8,9,10,10aβ-octahydronaphtho[1,2,3-cd]indole; 102045-13-6; Naphtho[1,2,3-cd]indole, 8β-chloro-9α-ethenyl-2,3,6,6aα,7,8,9,10,10aβ-octahydro-10α-isocyano-6,6,9-trimethyl-, (6aS,10aR)-; (6aS,10aR)-8β-Chloro-9α-ethenyl-10α-isocyano-6,6,9-trimethyl-2,3,6,6a,7,8,9,10,10a-octahydronaphtho[1,2,3-cd]indole
EINECS	Contact for details

Quality Control

Our [6As,(-)]-8β-Chloro-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aβ-Octahydro-10α-Isocyano-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and spectroscopic data are provided to guarantee traceability and support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C under an inert atmosphere. Allow the container to reach room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.