Description

(4-Bromoanilinomethylene)Malonic Acid Diethyl Ester is a specialized brominated aniline derivative and a key malonic ester synthon used in advanced organic synthesis. This compound matters as a versatile building block for constructing complex heterocyclic frameworks and pharmaceutical intermediates, particularly in the development of active pharmaceutical ingredients (APIs). It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for complex coupling and cyclization reactions.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those containing brominated aromatic and heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the bromoaniline moiety imparts specific biological activity.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other performance chemicals requiring precise molecular architecture.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for developing new synthetic routes involving Knoevenagel condensation or malonate chemistry.
• Material Science Research: Investigated as a monomer or precursor for functional organic materials and polymers with tailored electronic properties.

Basic Information

Product Name	(4-Bromoanilinomethylene)Malonic Acid Diethyl Ester
CAS No.	101937-44-4
Molecular Formula	C₁₄H₁₆BrNO₄
Molecular Weight	342.19 g/mol
Synonyms	Diethyl (4-Bromoanilinomethylene)malonate; Diethyl 2-[(4-Bromophenyl)amino]methylene]malonate; (4-Bromophenylamino)methylene-malonic Acid Diethyl Ester; Propanedioic acid, [(4-bromophenyl)amino]methylene-, diethyl ester; Malonic acid, (4-bromoanilinomethylene)-, diethyl ester; 4-Bromo-N-[(diethoxycarbonyl)methylene]aniline
EINECS	Contact for details

Quality Control

Our (4-Bromoanilinomethylene)Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.