Description

4-(Trifluoromethyl)Phenylglyoxal Hydrate is a versatile and high-value fluorinated building block in organic synthesis. Its core value lies in the reactive glyoxal moiety combined with the electron-withdrawing trifluoromethyl group, making it a critical precursor for synthesizing complex heterocycles and fine chemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various heterocyclic compounds, including imidazoles, quinoxalines, and other nitrogen-containing scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the CF3 group can enhance metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the synthesis of fluorinated organic molecules for electronic materials, liquid crystals, and polymers with unique properties.
• Chemical Biology Probes: Useful for modifying peptides or creating fluorescent tags and other molecular probes due to its reactive carbonyl groups.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences and specialty chemical sectors.

Basic Information

Product Name	4-(Trifluoromethyl)Phenylglyoxal Hydrate
CAS No.	101906-05-2
Molecular Formula	C9H5F3O3 • xH2O
Molecular Weight	218.13 (Anhydrous basis)
Synonyms	2-Oxo-2-[4-(trifluoromethyl)phenyl]acetaldehyde Hydrate; 4-(Trifluoromethyl)benzoylformaldehyde Hydrate; α-Oxo-4-(trifluoromethyl)benzeneacetaldehyde Hydrate; 4-Trifluoromethylphenylglyoxal Hydrate; 1-(4-Trifluoromethylphenyl)-1,2-ethanedione Hydrate; 4-CF3-Phenylglyoxal Hydrate; (4-Trifluoromethylphenyl)oxoacetaldehyde Hydrate
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Phenylglyoxal Hydrate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. While typically supplied at technical or research grades, production can be aligned with specific customer requirements. Certificates of Analysis (COA) detailing purity, identity, and relevant parameters are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.