Description

2,2,2-Trifluoro-1-(5-Nitro-3-Indolyl)Ethanone is a specialized fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a nitro group and a trifluoroacetyl moiety, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLEDs and semiconductors.
• Fluorine Chemistry: An important reagent for introducing the trifluoroacetyl group into complex molecular frameworks in medicinal and synthetic chemistry.
• Chemical Biology: Utilized as a probe or tag in biochemical research due to its distinct spectroscopic and reactivity profile.
• Academic & R&D: A valuable compound for methodological development and exploration of new reaction pathways in university and industrial research laboratories.

Basic Information

Product Name	2,2,2-Trifluoro-1-(5-Nitro-3-Indolyl)Ethanone
CAS No.	101832-10-4
Molecular Formula	C10H5F3N2O3
Molecular Weight	258.16 g/mol
Synonyms	1-(5-Nitro-1H-indol-3-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(5-nitro-1H-indol-3-yl)ethanone; 5-Nitro-3-trifluoroacetylindole; 3-Trifluoroacetyl-5-nitroindole; 2,2,2-Trifluoro-1-(5-nitroindol-3-yl)ethanone; 1-(5-Nitroindol-3-yl)-2,2,2-trifluoroethanone; 5-Nitro-3-indolyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(5-Nitro-3-Indolyl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.