Description

m-Peg7-Ch2Cooh is a monodisperse, heterobifunctional polyethylene glycol (PEG) derivative featuring a carboxylic acid group at one terminus and a methoxy group at the other. This precise molecular architecture is critical for creating stable, hydrophilic linkers in advanced bioconjugation and pharmaceutical formulation. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity, functionalized PEGs for developing next-generation therapeutics and diagnostics.

Application

• Bioconjugation and Drug Delivery: Serves as a key linker for attaching therapeutic payloads (e.g., drugs, proteins, peptides) to targeting molecules like antibodies or nanoparticles, enhancing solubility and circulation time.
• PEGylation Reagent: Used to modify the surface of proteins, peptides, and other biomolecules to improve their pharmacokinetic properties, stability, and reduce immunogenicity.
• Hydrogel and Biomaterial Synthesis: Acts as a functional monomer or cross-linker for creating biocompatible hydrogels with tailored properties for tissue engineering and controlled release applications.
• Surface Functionalization: Employed to introduce carboxylic acid groups onto surfaces (e.g., nanoparticles, sensors, chips) for subsequent covalent immobilization of biomolecules.
• Diagnostic Reagent Development: Utilized in the synthesis of contrast agents, fluorescent probes, and other diagnostic tools where a stable, hydrophilic spacer is required.
• Polymer Chemistry: Functions as a macro-initiator or macromonomer for the synthesis of well-defined block copolymers with specific functional end-groups.

Basic Information

Product Name	m-Peg7-Ch2Cooh
CAS No.	101791-31-5
Molecular Formula	C18H36O10
Molecular Weight	412.48 g/mol
Synonyms	mPEG7-COOH; Methoxy-PEG7-acetic acid; 2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid; α-Methoxy-ω-carboxymethylheptaethylene glycol; Heptaethylene glycol monomethyl ether acetic acid; 8-Methoxy-3,6,9,12,15,18,21-heptaoxatricosanoic acid; m-PEG7-Acid; CH3O-(CH2CH2O)7-CH2COOH
EINECS	Contact for details

Quality Control

Our m-Peg7-Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive applications like bioconjugation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Acid Value (Titration)	Contact for details
Molecular Weight (MS)	412.48 ± 5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.