Description

2,6-Difluorophenylacetone is a key fluorinated aromatic building block and intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce difluorophenyl motifs into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluorophenyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials to modify solubility and electronic properties.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses serving the life sciences sector.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	2,6-Difluorophenylacetone
CAS No.	101712-20-3
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,6-Difluorophenyl)propan-2-one; 2,6-Difluorophenylacetone; 2',6'-Difluoropropiophenone; 2-Propanone, 1-(2,6-difluorophenyl)-; 2,6-DFPA; α,2,6-Trifluoroacetophenone (common misnomer); 2,6-Difluoro-α-methylbenzyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2,6-Difluorophenylacetone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed and stored in a moisture-free environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.