Description

2-(tert-Butyldimethylsilyloxy)Ethanamine is a versatile organosilicon-protected amino alcohol derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in its dual functionality, where the silyl ether group provides excellent protection for the hydroxyl moiety, while the primary amine is available for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules, particularly those requiring protected amino alcohol motifs.
• Peptide Mimetics & Conjugation: Used in the preparation of peptide analogs and for the chemical conjugation of payloads in bioconjugation and prodrug development.
• Agrochemical Synthesis: Employed as a building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced properties.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Surface Modification & Silane Chemistry: Utilized in the functionalization of surfaces (e.g., silica, glass) and polymers to introduce amine-reactive sites.
• Polymer & Resin Functionalization: Acts as a monomer or cross-linking agent for producing specialty polymers with tailored mechanical and chemical properties.

Basic Information

Product Name	2-(tert-Butyldimethylsilyloxy)Ethanamine
CAS No.	101711-55-1
Molecular Formula	C8H21NOSi
Molecular Weight	175.35 g/mol
Synonyms	2-[(tert-Butyldimethylsilyl)oxy]ethanamine; 2-(TBDMSO)ethanamine; N-(2-Hydroxyethyl)-N-(tert-butyldimethylsilyl)amine; 2-Aminoethyl tert-butyldimethylsilyl ether; 2-(tert-Butyldimethylsiloxy)ethylamine; Ethanol, 2-amino-, 1-(1,1-dimethylethyl)dimethylsilyl ether; TBDMS-protected ethanolamine
EINECS	Contact for details

Quality Control

Our 2-(tert-Butyldimethylsilyloxy)Ethanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.