Description

(2R)-2-[(2-Methylphenoxy)Methyl]Oxirane is a chiral epoxide building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined oxirane ring, which serves as a versatile electrophilic center for nucleophilic ring-opening reactions to introduce chiral complexity. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of enantiomerically pure active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for constructing active pharmaceutical ingredients (APIs) requiring specific stereochemistry, particularly in cardiovascular and central nervous system drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in epoxidation or hydroxylation reactions.
• Fine Chemical Production: Employed in the multistep synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with tailored chiral properties or specific reactivity.

Basic Information

Product Name	(2R)-2-[(2-Methylphenoxy)Methyl]Oxirane
CAS No.	101693-39-4
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(R)-(-)-Glycidyl o-tolyl ether; (R)-2-[(2-Methylphenoxy)methyl]oxirane; (R)-Glycidyl 2-methylphenyl ether; (2R)-2-[(2-Methylphenoxy)methyl]oxirane; (-)-Glycidyl o-cresyl ether; (R)-o-Cresyl glycidyl ether; (R)-1,2-Epoxy-3-(o-tolyloxy)propane; (R)-2-Methylphenyl glycidyl ether
EINECS	Contact for details

Quality Control

Our (2R)-2-[(2-Methylphenoxy)Methyl]Oxirane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon), please contact us.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.