Description

2-Penten-1-One, 2-Fluoro-4,4-Dimethyl-1-Phenyl-, (Z)- (9Ci) is a specialized fluorinated ketone building block with a defined stereochemistry. This compound is valued for its unique molecular structure, which combines a reactive α,β-unsaturated ketone moiety with a fluorine atom and a phenyl group, making it a versatile intermediate for advanced synthesis. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry and crop protection research.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for complex organic transformations, including Michael additions, cyclizations, and asymmetric synthesis.
• Ligand and Catalyst Development: The defined (Z)-configuration and functional groups make it a candidate for developing chiral ligands and organocatalysts.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex aroma chemicals due to its ketone backbone and phenyl substituent.

Basic Information

Product Name	2-Penten-1-One, 2-Fluoro-4,4-Dimethyl-1-Phenyl-, (Z)- (9Ci)
CAS No.	101560-11-6
Molecular Formula	C13H15FO
Molecular Weight	206.26 g/mol
Synonyms	(Z)-2-Fluoro-4,4-dimethyl-1-phenyl-2-penten-1-one; (Z)-1-Phenyl-2-fluoro-4,4-dimethyl-2-penten-1-one; 2-Fluoro-4,4-dimethyl-1-phenyl-2-penten-1-one, (Z)-; 2-Penten-1-one, 2-fluoro-4,4-dimethyl-1-phenyl-, (Z)-; (Z)-2-Fluoro-4,4-dimethyl-1-phenylpent-2-en-1-one; 101560-11-6; (Z)-isomer of 2-Fluoro-4,4-dimethyl-1-phenyl-2-penten-1-one
EINECS	Contact for details

Quality Control

Our production of 2-Penten-1-One, 2-Fluoro-4,4-Dimethyl-1-Phenyl-, (Z)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including GC, HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Isomeric Purity ((Z)-isomer)	≥ 98.0% (by GC or HPLC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.