Description

cis-8-Methoxy-1,2,3,4,4A,5,6,8A-Octahydronaphthalene is a high-purity, specialized organic intermediate featuring a methoxylated decalin core structure. This compound matters for its role as a critical chiral building block in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing complex odorants and flavor compounds with woody, amber, or musk characteristics.
• Material Science Research: Investigated as a monomer or modifying agent for creating novel polymers with specific thermal or optical properties.
• Academic & Contract Research: Employed in organic chemistry laboratories for methodological studies in asymmetric synthesis and catalysis.
• Fine Chemical Production: Utilized in custom synthesis and scale-up projects for clients requiring high-purity, structurally complex intermediates.

Basic Information

Product Name	cis-8-Methoxy-1,2,3,4,4A,5,6,8A-Octahydronaphthalene
CAS No.	101555-41-3
Molecular Formula	C₁₁H₁₈O
Molecular Weight	166.26 g/mol
Synonyms	8-Methoxy-cis-decalin; (4aS,8aR)-8-Methoxy-1,2,3,4,4a,5,6,8a-octahydronaphthalene; cis-8-Methoxydecahydronaphthalene; 8-Methoxy-1,2,3,4,4a,5,6,8a-octahydronaphthalene (cis); Methoxydecalin (cis-8- isomer); Decalin, 8-methoxy-, cis-; Chiral methoxydecalin intermediate
EINECS	Contact for details

Quality Control

Every batch of cis-8-Methoxy-1,2,3,4,4A,5,6,8A-Octahydronaphthalene is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by GC, HPLC, and NMR. Our quality commitment ensures the material meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.