Description

(Z)-2-Methyl-2-Butenoic Acid (1Ar,3S,4R,5Ar,8As,9R,10Ar)-Dodecahydro-3-Hydroxy-4,10A-Dimethyl-8-Methylene-7-Oxooxireno[5,6]Cyclodeca[1,2-B]Furan-9-Yl Ester is a high-purity, complex organic ester with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate or research chemical. Its intricate molecular architecture makes it a valuable building block for the synthesis of novel compounds in medicinal chemistry. This product is essential for R&D laboratories and production facilities focused on developing specialty fine chemicals, particularly in the pharmaceutical and agrochemical sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in complex natural product derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and as a precursor for novel drug candidates targeting specific biological pathways.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, high-specificity pesticides or herbicides.
• Organic Synthesis & Catalysis: Serves as a sophisticated substrate or ligand in asymmetric synthesis and catalytic reactions for academic and industrial research.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(Z)-2-Methyl-2-Butenoic Acid (1Ar,3S,4R,5Ar,8As,9R,10Ar)-Dodecahydro-3-Hydroxy-4,10A-Dimethyl-8-Methylene-7-Oxooxireno[5,6]Cyclodeca[1,2-B]Furan-9-Yl Ester
CAS No.	101527-88-2
Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.43 g/mol
Synonyms	Tiglic Acid, (1Ar,3S,4R,5Ar,8As,9R,10Ar)-Dodecahydro-3-Hydroxy-4,10A-Dimethyl-8-Methylene-7-Oxooxireno[5,6]Cyclodeca[1,2-B]Furan-9-Yl Ester; (Z)-2-Methylbut-2-enoic Acid Artemisinyl Ester Derivative; Artesunate Related Compound; 101527-88-2; Dihydroartemisinin Tiglate Ester; Oxireno[5,6]cyclodeca[1,2-b]furan Derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.