Description

8-Chlorophthalazin-1(2H)-One is a versatile heterocyclic building block and key synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized phthalazinone core, which serves as a crucial scaffold for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes like poly(ADP-ribose) polymerase (PARP) and phosphodiesterases (PDEs).
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or precursor for creating high-performance polymers, dyes, and photoactive materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Ligand & Catalyst Development: Useful for synthesizing specialized ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Product Name	8-Chlorophthalazin-1(2H)-One
CAS No.	101494-94-4
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	8-Chloro-1,2-dihydrophthalazin-1-one; 8-Chloro-1H-phthalazin-1-one; 8-Chlorophthalazinone; 1(2H)-Phthalazinone, 8-chloro-; 8-Chloro-2H-phthalazin-1-one; 8-Chloro-1-phthalazinone; 8-Chloro-1,2-dihydro-1-phthalazinone
EINECS	Contact for details

Quality Control

Our 8-Chlorophthalazin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.