Description

2-Cycloocten-1-One, 2-Fluoro-8-Methyl- is a fluorinated cyclic enone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an α,β-unsaturated ketone and a fluorine substituent, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorinated cyclooctenone core contributes to biological activity.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, such as asymmetric catalysis, cycloaddition reactions, and fluorine chemistry studies.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex macrocyclic musk analogs and other specialty aroma chemicals.
• Ligand & Catalyst Design: Useful scaffold for developing novel chiral ligands and organocatalysts due to its rigid, functionalizable backbone.

Basic Information

Product Name	2-Cycloocten-1-One, 2-Fluoro-8-Methyl-
CAS No.	101128-37-4
Molecular Formula	C9H13FO
Molecular Weight	156.20 g/mol
Synonyms	2-Fluoro-8-methylcyclooct-2-en-1-one; 8-Methyl-2-fluorocyclooct-2-en-1-one; 2-Fluoro-8-methyl-2-cycloocten-1-one; 2-Cycloocten-1-one, 2-fluoro-8-methyl-; Fluorinated Cyclooctenone Derivative; F-Methyl Cyclooctenone
EINECS	Contact for details

Quality Control

Our 2-Cycloocten-1-One, 2-Fluoro-8-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.