Description

1H-Pyrazole-3-Carboxylicacid,4,5-Dihydro-4-Methyl-,Methylester(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for developing novel pharmacologically active molecules, particularly in medicinal chemistry and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex pyrazole-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a precursor for dyes, pigments, and other high-value specialty chemicals.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in heterocyclic chemistry and reaction methodology development.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylicacid,4,5-Dihydro-4-Methyl-,Methylester(9Ci)
CAS No.	101080-10-8
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	4,5-Dihydro-4-methyl-1H-pyrazole-3-carboxylic acid methyl ester; Methyl 4,5-dihydro-4-methyl-1H-pyrazole-3-carboxylate; 4-Methyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester; 1H-Pyrazole-3-carboxylic acid, 4,5-dihydro-4-methyl-, methyl ester; 4-Methyl-2-pyrazoline-3-carboxylic acid methyl ester; 101080-10-8; Methyl 4-methyl-4,5-dihydro-1H-pyrazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carboxylicacid,4,5-Dihydro-4-Methyl-,Methylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.