Description

2-Chloroisonicotinaldehyde is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde and a chloro substituent on the pyridine ring, makes it a valuable precursor for constructing complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological systems and enzyme functions.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and academic laboratories exploring new chemical space.

Basic Information

Product Name	2-Chloroisonicotinaldehyde
CAS No.	101066-61-9
Molecular Formula	C6H4ClNO
Molecular Weight	141.55 g/mol
Synonyms	2-Chloro-4-formylpyridine; 2-Chloro-4-pyridinecarboxaldehyde; 4-Pyridinecarboxaldehyde, 2-chloro-; Isonicotinaldehyde, 2-chloro-; 2-Chloropyridine-4-carbaldehyde; 2-Chloroisonicotinic aldehyde; 2-Chloro-4-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloroisonicotinaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and impurity profiles. We support our clients' regulatory needs and can provide material suitable for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.