Description

2-(1,3-Thiazol-2-Yl)Acetonitrile is a versatile heterocyclic building block featuring both a thiazole ring and a reactive nitrile group. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiazole motifs for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole heterocycle.
• Material Science Research: Serves as a building block for creating advanced functional materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents due to its reactive handle.
• Dye & Pigment Intermediate: Utilized in the synthesis of heterocyclic dyes and organic pigments for specialized coloring applications.

Basic Information

Product Name	2-(1,3-Thiazol-2-Yl)Acetonitrile
CAS No.	101010-74-6
Molecular Formula	C5H4N2S
Molecular Weight	124.16 g/mol
Synonyms	2-Thiazoleacetonitrile; (Thiazol-2-yl)acetonitrile; 2-Cyanomethylthiazole; 2-(2-Thiazolyl)acetonitrile; 2-Thiazolylacetonitrile; Acetonitrile, 2-(2-thiazolyl)-; 2-(1,3-Thiazol-2-yl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 2-(1,3-Thiazol-2-Yl)Acetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.