Description

1,3,2-Dioxaborinane, 6-tert-Butyl-2-Methoxy-4,4-Bis(Trifluoromethyl)- is a specialized organoboron compound featuring a unique cyclic dioxaborinane structure with trifluoromethyl and tert-butyl substituents. This chemical is valued for its role as a versatile building block and reagent in advanced synthetic chemistry, particularly where the introduction of boron and fluorine-containing moieties is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of boron-containing drug candidates, including potential protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the boron and fluorine groups can enhance biological activity and environmental stability.
• Materials Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers, resins, and functional materials with specific optical or electronic properties.
• Suzuki-Miyaura Cross-Coupling: Functions as an organoboron reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, a fundamental transformation in fine chemical synthesis.
• Fluorine Chemistry Building Block: The bis(trifluoromethyl) group makes it a valuable source of CF3 units for introducing fluorinated segments into target molecules to modulate lipophilicity and metabolic stability.
• Catalyst and Ligand Development: Explored for use in designing novel catalysts and ligands for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	1,3,2-Dioxaborinane, 6-tert-Butyl-2-Methoxy-4,4-Bis(Trifluoromethyl)-
CAS No.	100991-78-4
Molecular Formula	C10H15BF6O3
Molecular Weight	308.03 g/mol
Synonyms	6-tert-Butyl-2-methoxy-4,4-bis(trifluoromethyl)-1,3,2-dioxaborinane; 2-Methoxy-6-tert-butyl-4,4-bis(trifluoromethyl)-1,3,2-dioxaborinane; 4,4-Bis(trifluoromethyl)-6-tert-butyl-2-methoxy-1,3,2-dioxaborinane; tert-Butyl Methylene Bis(trifluoromethyl)boronate (cyclic); Cyclic tert-butyl methylene bis(trifluoromethyl)boronate
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborinane, 6-tert-Butyl-2-Methoxy-4,4-Bis(Trifluoromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced spectroscopic and chromatographic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.