Description

Diethanolamine-(3R)-(+)-Tetrahydrofuranylboronate is a specialized chiral organoboron reagent, a key intermediate in modern synthetic chemistry. Its value lies in enabling highly stereoselective transformations, crucial for constructing complex molecules with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Asymmetric Synthesis: A critical chiral building block for the stereoselective formation of carbon-carbon and carbon-heteroatom bonds.
• Pharmaceutical Intermediate: Used in the research and production of chiral drug candidates, especially those requiring specific (3R) stereochemistry.
• Cross-Coupling Reactions: Serves as a boronic ester reagent in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Catalyst and Ligand Development: A precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products, agrochemicals, and specialty chemicals.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis laboratories worldwide.

Basic Information

Product Name	Diethanolamine-(3R)-(+)-Tetrahydrofuranylboronate
CAS No.	100858-40-0
Molecular Formula	C8H16BNO3
Molecular Weight	185.03 g/mol
Synonyms	(3R)-Tetrahydro-3-furanylboronic acid diethanolamine ester; (R)-(+)-Tetrahydro-3-furanylboronic acid diethanolamine ester; (3R)-(+)-Tetrahydrofuranylboronic Acid Diethanolamine Ester; (R)-Tetrahydrofuran-3-ylboronic Acid DEA Ester; Diethanolamine (3R)-Tetrahydro-3-furanylboronate; B-(3R)-Tetrahydro-3-furanylboronic Acid Diethanolamine Complex; (R)-3-THF-Boronic Acid DEA Ester
EINECS	Contact for details

Quality Control

Our Diethanolamine-(3R)-(+)-Tetrahydrofuranylboronate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.