Description

4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-2-One is a valuable, protected boronic ester derivative, widely utilized as a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in enabling efficient and selective carbon-carbon bond formation, particularly in challenging coupling environments. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing ketone or complex alkylboronate functionalities.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for palladium-catalyzed cross-coupling with aryl/vinyl halides, a cornerstone reaction in medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific boronate-containing scaffolds.
• Advanced Material Precursor: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where precise molecular architecture is critical.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of molecular probes and sensors due to its reactive ketone and protected boronic acid groups.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D laboratories exploring new methodologies in synthetic organic chemistry.

Basic Information

Product Name	4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-2-One
CAS No.	100818-32-4
Molecular Formula	C10H19BO3
Molecular Weight	198.07 g/mol
Synonyms	2-Butanone, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)butan-2-one; 2-(3-Oxobutyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-Oxobutyl)boronate; 3-Oxobutylboronic Acid Pinacol Ester; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)butan-3-one; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-butanone
EINECS	Contact for details

Quality Control

Our 4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Butan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent performance in sensitive applications like cross-coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.