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Ht-2 Toxin 3-Glucuronide CAS NO 100690-35-5


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CAS No.:100690-35-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ht-2 Toxin 3-Glucuronide is a crucial conjugated metabolite of the mycotoxin HT-2, formed via glucuronidation, a primary detoxification pathway in biological systems. This compound is of significant importance for analytical and diagnostic applications, serving as a key biomarker and reference standard for the accurate detection and quantification of HT-2 toxin exposure. It is primarily needed by research institutions, diagnostic laboratories, and food safety agencies engaged in mycotoxin analysis, toxicology studies, and the development of immunoassays or LC-MS/MS methods for food and feed safety compliance.

Application

  • Biomarker Reference Standard: Used as a certified reference material (CRM) for the calibration and validation of analytical methods detecting HT-2 toxin metabolites in biological samples (e.g., urine, blood).
  • Food & Feed Safety Testing: Essential for developing and performing accurate LC-MS/MS or ELISA tests to monitor HT-2 toxin contamination and ensure regulatory compliance in grains and animal feed.
  • Toxicological Research: Employed in studies to investigate the metabolism, pharmacokinetics, and biological effects of HT-2 toxin and its conjugates.
  • Diagnostic Kit Development: Serves as a critical antigen or hapten in the production of antibodies for immunoassay kits designed to screen for trichothecene mycotoxin exposure.
  • Method Development & Validation: Used by analytical chemists to establish new protocols, confirm method specificity, and ensure accurate quantification in complex matrices.
  • Quality Control & Proficiency Testing: Incorporated into QC samples and proficiency testing schemes for laboratories to benchmark their analytical performance against peers.

Basic Information

Product Name Ht-2 Toxin 3-Glucuronide
CAS No. 100690-35-5
Molecular Formula C29H42O13
Molecular Weight 598.64 g/mol
Synonyms HT-2 toxin 3-β-D-Glucuronide; HT2-GlcA; 15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en-7-one 3-Glucuronide; HT-2-Glucuronide; HT-2 toxin glucuronide; HT2-3-Gluc; 3-Glucuronide of HT-2 Toxin
EINECS Contact for details

Quality Control

Our Ht-2 Toxin 3-Glucuronide is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency, suitable for sensitive analytical applications. Each batch is thoroughly characterized using advanced spectroscopic and chromatographic techniques, including NMR and HPLC, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Solubility Soluble in methanol, acetonitrile, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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