Description

1-Propanone, 2-Bromo-1-Phenyl-, (S)- (9Ci) is a high-value chiral building block characterized by its brominated phenylacetone structure and specific (S)-enantiomeric configuration. This compound is essential for the synthesis of complex molecules where stereochemistry is critical for biological activity or material properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for creating novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Serves as a versatile electrophile or precursor in stereoselective carbon-carbon bond-forming reactions, such as alkylations and Reformatsky-type reactions.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis or as a precursor for complex molecular scaffolds in catalyst design.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty agrochemicals, flavors, fragrances, and advanced organic materials where optical purity is required.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways in process chemistry.

Basic Information

Product Name	1-Propanone, 2-Bromo-1-Phenyl-, (S)- (9Ci)
CAS No.	100679-76-3
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	(S)-2-Bromo-1-phenylpropan-1-one; (S)-2-Bromopropiophenone; (S)-α-Bromopropiophenone; (S)-Bromo-1-phenyl-1-propanone; (S)-1-Phenyl-2-bromopropanone; (S)-2-Bromo-1-phenylethanone, methyl-; (S)-Bromopropiophenone; L-2-Bromopropiophenone
EINECS	Contact for details

Quality Control

Our 1-Propanone, 2-Bromo-1-Phenyl-, (S)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and physical parameters is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfers should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.