Description

Ethanone, 2,2,2-Trifluoro-1-[2-(Hydroxymethyl)Phenyl]- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a benzyl alcohol moiety, making it a valuable fluorinated building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring the introduction of both trifluoroacetyl and hydroxymethyl functional groups into complex molecular architectures. It is primarily sought after by the pharmaceutical, agrochemical, and advanced materials industries for applications in medicinal chemistry, ligand synthesis, and the development of novel fluorinated polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for introducing the metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, leveraging the hydroxymethyl group for further functionalization.
• Advanced Material Precursor: Employed in the synthesis of fluorinated monomers for specialty polymers, coatings, and liquid crystals with unique thermal and chemical resistance properties.
• Chemical Biology Probe: Utilized in the design of activity-based probes and inhibitors for studying enzyme mechanisms, especially serine hydrolases.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[2-(Hydroxymethyl)Phenyl]- (9Ci)
CAS No.	100656-08-4
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	2,2,2-Trifluoro-1-[2-(hydroxymethyl)phenyl]ethanone; 2'-(Hydroxymethyl)-2,2,2-trifluoroacetophenone; 1-(2-Hydroxymethylphenyl)-2,2,2-trifluoroethanone; α,α,α-Trifluoro-2-(hydroxymethyl)acetophenone; 2-(Trifluoroacetyl)benzyl alcohol; (2-(Hydroxymethyl)phenyl)(trifluoromethyl)methanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[2-(Hydroxymethyl)Phenyl]- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and commercial use. All materials are subjected to rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.