Description

Ethyl 6-(tert-Butyl)-3-Cyano-2-Hydroxyisonicotinate is a specialized pyridine derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its unique molecular scaffold, which combines a sterically hindered tert-butyl group with reactive cyano and ester functionalities, enabling precise chemical modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting specific biological pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its pyridine core for bioactivity.
• Chemical Research & Development: Serves as a versatile precursor for creating complex heterocyclic libraries and exploring new chemical spaces in academic and industrial labs.
• Material Science: Potential intermediate in the synthesis of specialty chemicals, ligands for catalysis, or organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production of client-specific target molecules.

Basic Information

Product Name	Ethyl 6-(tert-Butyl)-3-Cyano-2-Hydroxyisonicotinate
CAS No.	100616-09-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	Ethyl 6-tert-butyl-3-cyano-2-hydroxypyridine-4-carboxylate; 2-Hydroxy-6-(1,1-dimethylethyl)-3-cyano-4-pyridinecarboxylic Acid Ethyl Ester; 4-Pyridinecarboxylic acid, 3-cyano-2-hydroxy-6-(1,1-dimethylethyl)-, ethyl ester; Ethyl 2-hydroxy-6-tert-butyl-3-cyanopyridine-4-carboxylate; 6-tert-Butyl-3-cyano-2-hydroxyisonicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-(tert-Butyl)-3-Cyano-2-Hydroxyisonicotinate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.