Description

8-Exo-Iodo-2-Azabicyclo[3.3.0]Octane-3-One is a high-value, iodinated bicyclic lactam building block of significant interest in advanced organic synthesis. Its unique fused ring structure and reactive iodine substituent make it a critical intermediate for constructing complex nitrogen-containing heterocycles. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel, biologically active nitrogen heterocycles with potential therapeutic applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex bicyclic scaffold.
• Methodology Development: Serves as a model substrate in organic chemistry research for studying new cross-coupling reactions and C-N bond formation techniques.
• Ligand & Catalyst Synthesis: A precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	8-Exo-Iodo-2-Azabicyclo[3.3.0]Octane-3-One
CAS No.	100556-58-9
Molecular Formula	C7H10INO
Molecular Weight	251.07 g/mol
Synonyms	8-Iodo-2-azabicyclo[3.3.0]octan-3-one (exo-); 8-exo-Iodo-2-azabicyclo[3.3.0]octan-3-one; (3aR,6aS)-8-Iodo-2-azabicyclo[3.3.0]octan-3-one; 2-Azabicyclo[3.3.0]octan-3-one, 8-iodo-, (3aR,6aS)-rel-; Iodinated bicyclic lactam; 8-Iodohexahydro-1H-pyrrolo[3,4-c]pyrrol-1-one
EINECS	Contact for details

Quality Control

Our 8-Exo-Iodo-2-Azabicyclo[3.3.0]Octane-3-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.