Description

1-(o-Chlorophenyl)-4,4,4-Trifluoro-3-(Trifluoromethyl)-2-Buten-1-Ol is a high-value fluorinated organic intermediate characterized by its unique chlorophenyl and trifluoromethylbutenol structure. This compound is essential for synthesizing advanced molecules where the introduction of fluorine atoms and specific aromatic substitution patterns is critical for modulating biological activity and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorine-containing group improves efficacy and environmental profile.
• Material Science Precursor: Serves as a specialty monomer or additive in the research of advanced polymers and coatings with specific surface properties.
• Chemical Synthesis: Versatile intermediate for constructing complex organic frameworks in academic and industrial organic chemistry laboratories.
• Ligand & Catalyst Development: Potential starting material for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-(o-Chlorophenyl)-4,4,4-Trifluoro-3-(Trifluoromethyl)-2-Buten-1-Ol
CAS No.	100482-52-8
Molecular Formula	C11H7ClF6O
Molecular Weight	304.62 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)-γ,γ,γ-trifluorocrotonophenone; 1-(2-Chlorophenyl)-4,4,4-trifluoro-3-(trifluoromethyl)but-2-en-1-ol; o-Chloro-α-(trifluoromethyl)-γ,γ,γ-trifluorocrotonophenol; 2-Chloro-α-(trifluoromethyl)-γ,γ,γ-trifluorocrotonophenol; 1-(2-Chlorophenyl)-4,4,4-trifluoro-3-trifluoromethyl-2-buten-1-ol
EINECS	Contact for details

Quality Control

Our production of 1-(o-Chlorophenyl)-4,4,4-Trifluoro-3-(Trifluoromethyl)-2-Buten-1-Ol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.